De Clercq, Erik : rechercher sur Z-Library

Nature Reviews Drug Discovery

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 4.45 MB

english, 2002

Suramin: A potent inhibitor of the reverse transcriptase of RNA tumor viruses

Wang, Yali, De Clercq, Erik, Li, Guangdi

Journal:

Cancer Letters

Année:

1979

Langue:

english

Fichier:

PDF, 853 KB

english, 1979

Current and emerging non-nucleoside reverse transcriptase inhibitors (NNRTIs) for HIV-1 treatment

Journal:

Expert Opinion on Drug Metabolism & Toxicology

Année:

2019

Langue:

english

Fichier:

PDF, 1.36 MB

english, 2019

Relationship between the foot progression angle and eversion and exercise-related lower leg pain

Tine M Willems, Erik Witvrouw, Dirk De Clercq, Philip Roosen

Journal:

Journal of Foot and Ankle Research

Année:

2012

Langue:

english

Fichier:

PDF, 68 KB

english, 2012

Intrinsic gait-related risk factors for Achilles tendinopathy in novice runners: A prospective study

Ans Van Ginckel, Youri Thijs, Narmin Ghani Zadeh Hesar, Nele Mahieu, Dirk De Clercq, Philip Roosen, Erik Witvrouw

Journal:

Gait & Posture

Année:

2009

Langue:

english

Fichier:

PDF, 274 KB

english, 2009

Overview of Recent Strategic Advances in Medicinal Chemistry

Wu, Gaochan, Zhao, Tong, Kang, Dongwei, Zhang, Jian, Song, Yuning, Namasivayam, Vigneshwaran, Kongsted, Jacob, Pannecouque, Christophe, De Clercq, Erik, Poongavanam, Vasanthanathan, Liu, Xinyong, Zhan

Journal:

Dr. Wenjun Li, Yu Chang, Peng Zhan, Prof. Dr. Na Zhang, Prof. Dr. Xinyong Liu, Prof. Dr. Christophe Pannecouque, Prof. Dr. Erik De Clercq

Année:

2019

Langue:

english

Fichier:

PDF, 3.78 MB

english, 2019

Synthesis, In Vitro and In Vivo Release Kinetics, and Anti-HIV Activity of A Sustained-Release Prodrug (mPEG-AZT) of 3′-Azido-3′-deoxythymidine (AZT, Zidovudine)

Journal:

ChemMedChem

Année:

2010

Langue:

english

Fichier:

PDF, 337 KB

english, 2010

Therapy and short-term prophylaxis of poxvirus infections: historical background and perspectives

Johan Neyts, Erik De Clercq

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 141 KB

english, 2003

A 40-Year Journey in Search of Selective Antiviral Chemotherapy*

Annual Review of Pharmacology

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 3.90 MB

english, 2011

Antiviral drugs: current state of the art

Journal of Clinical Virology

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 304 KB

english, 2001

Suramin in the treatment of AIDS: Mechanism of action

Journal:

VERRELST, RUTH, DE CLERCQ, DIRK, WILLEMS, TINE MARIEKE, ROOSEN, PHILIP, WITROUW, ERIK

Année:

1987

Langue:

english

Fichier:

PDF, 499 KB

english, 1987

Contralateral Risk Factors Associated with Exertional Medial Tibial Pain in Women

Journal:

Medicine & Science in Sports & Exercise

Année:

2014

Langue:

english

Fichier:

PDF, 2.87 MB

english, 2014

Anti-HIV Drug Discovery and Development: Current Innovations and Future Trends

Zhan, Peng, Pannecouque, Christophe, De Clercq, Erik, Liu, Xinyong

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 3.58 MB

english, 2015

Tenofovir alafenamide (TAF) as the successor of tenofovir disoproxil fumarate (TDF)

Journal:

Biochemical Pharmacology

Année:

2016

Langue:

english

Fichier:

PDF, 643 KB

english, 2016

Design, synthesis and biological evaluation of novel acetamide-substituted doravirine and its prodrugs as potent HIV-1 NNRTIs

Wang, Zhao, Yu, Zhao, Kang, Dongwei, Zhang, Jian, Tian, Ye, Daelemans, Dirk, De Clercq, Erik, Pannecouque, Christophe, Zhan, Peng, Liu, Xinyong

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 1.57 MB

english, 2018

New Nucleoside Analogues for the Treatment of Hemorrhagic Fever Virus Infections

Chemistry – An Asian Journal

Journal:

Année:

2019

Langue:

english

Fichier:

PDF, 675 KB

english, 2019

In vitro, ex vivo, and in situ intestinal absorption characteristics of the antiviral ester prodrug adefovir dipivoxil

Pieter Annaert, Josef J. Tukker, Jan van Gelder, Lieve Naesens, Erik de Clercq, Guy van den Mooter, Renaat Kinget, Patrick Augustijns

Journal:

Journal of Pharmaceutical Sciences

Année:

2000

Langue:

english

Fichier:

PDF, 202 KB

english, 2000

1,2,3-Thiadiazole Thioacetanilides. Part 2 : Synthesis and Biological Evaluation of a New Series of 2-{[4-(3,4-Dichlorophenyl)-1,2,3-thiadiazol-5-yl]sulfanyl}acetanilides as HIV-1 Inhibitors

Peng Zhan, Xin-Yong Liu, Zhen-Yu Li, Zeng-Jun Fang, Christophe Pannecouque, Erik De Clercq

Journal:

Chemistry & Biodiversity

Année:

2010

Langue:

english

Fichier:

PDF, 330 KB

english, 2010

Synthesis and Antileishmanial Activity of (1,3-Benzothiazol-2-yl) Amino-9-(10H)-acridinone Derivatives.

Florence Delmas, Antonio Avellaneda, Carole Di Giorgio, Maxime Robin, Erik De Clercq, Pierre Timon-David, Jean-Pierre Galy

Journal:

ChemInform

Année:

2004

Fichier:

PDF, 15 KB

2004

Activity of the keggin polyoxotungstate pm-19 against herpes simplex virus type 2 infection in immunosuppressed mice: Role of peritoneal macrophage activation

Dr. Satoru Ikeda, Shigeki Nishiya, Akihiro Yamamoto, Toshihiro Yamase, Chiaki Nishimura, Erik De Clercq

Journal:

Journal of Medical Virology

Année:

1993

Langue:

english

Fichier:

PDF, 521 KB

english, 1993

Synthesis and antiviral evaluation of benzimidazoles, quinoxalines and indoles from dehydroabietic acid

Tatiana Fonseca, Bárbara Gigante, M.Matilde Marques, Thomas L. Gilchrist, Erik De Clercq

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 280 KB

english, 2004

The novel C-5 aryl, alkenyl, and alkynyl substituted uracil derivatives of l-ascorbic acid: Synthesis, cytostatic, and antiviral activity evaluations

Tatjana Gazivoda, Silvana Raić-Malić, Marko Marjanović, Marijeta Kralj, Krešimir Pavelić, Jan Balzarini, Erik De Clercq, Mladen Mintas

Journal:

Florence Delmas, Antonio Avellaneda, Carole Di Giorgio, Maxime Robin, Erik De Clercq, Pierre Timon-David, Jean-Pierre Galy

Année:

2007

Langue:

english

Fichier:

PDF, 220 KB

english, 2007

Synthesis and antileishmanial activity of (1,3-benzothiazol-2-yl) amino-9-(10H)-acridinone derivatives

Journal:

Güniz Küçükgüzel, Ayla Kocatepe, Erik De Clercq, Fikrettin Şahin, Medine Güllüce

Année:

2004

Langue:

english

Fichier:

PDF, 226 KB

english, 2004

Synthesis and biological activity of 4-thiazolidinones, thiosemicarbazides derived from diflunisal hydrazide

Journal:

İlkay Küçükgüzel, Esra Tatar, Ş. Güniz Küçükgüzel, Sevim Rollas, Erik De Clercq

Année:

2006

Langue:

english

Fichier:

PDF, 304 KB

english, 2006

Synthesis of some novel thiourea derivatives obtained from 5-[(4-aminophenoxy)methyl]-4-alkyl/aryl-2,4-dihydro-3H-1,2,4-triazole-3-thiones and evaluation as antiviral/anti-HIV and anti-tuberculosis agents

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 394 KB

english, 2008

Structure–activity relationships for dipeptide prodrugs of acyclovir: Implications for prodrug design

Cledir R. Santos, Rita Capela, Cláudia S.G.P. Pereira, Emília Valente, Luís Gouveia, Christophe Pannecouque, Erik De Clercq, Rui Moreira, Paula Gomes

Journal:

María-Jesús Pérez-Pérez, Erik De Clercq, Piet Herdewijn

Année:

2009

Langue:

english

Fichier:

PDF, 389 KB

english, 2009

Synthesis and antiviral activity of 2-deoxy-1,5-anhydro-D-mannitol nucleosides containing a pyrimidine base moiety

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

1996

Langue:

english

Fichier:

PDF, 210 KB

english, 1996

Synthesis, antimicrobial and antiviral evaluation of substituted imidazole derivatives

Deepika Sharma, Balasubramanian Narasimhan, Pradeep Kumar, Vikramjeet Judge, Rakesh Narang, Erik De Clercq, Jan Balzarini

Journal:

Krishnan Suresh Kumar, Swastika Ganguly, Ravichandran Veerasamy, Erik De Clercq

Année:

2009

Langue:

english

Fichier:

PDF, 225 KB

english, 2009

Synthesis, antiviral activity and cytotoxicity evaluation of Schiff bases of some 2-phenyl quinazoline-4(3)H-ones

Journal:

Nature Reviews Drug Discovery

Année:

2010

Langue:

english

Fichier:

PDF, 170 KB

english, 2010

Acute Encephalitis, a Poliomyelitis-like Syndrome and Neurological Sequelae in a Hamster Model for Flavivirus Infections

Pieter Leyssen, Romaric Croes, Philipp Rau, Sabine Heiland, Erik Verbeken, Raphael Sciot, Jan Paeshuyse, Nathalie Charlier, Erik De Clercq, Uta Meyding-Lamadé, Johan Neyts

Journal:

Brain Pathology

Année:

2003

Langue:

english

Fichier:

PDF, 1.15 MB

english, 2003

Three decades of antiviral drugs

Clercq, Erik De

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 107 KB

english, 2007

Antiviral properties of new arylsulfone derivatives with activity against human betaherpesviruses

Lieve Naesens, Chad E. Stephens, Graciela Andrei, Arianna Loregian, Leen De Bolle, Robert Snoeck, J. Walter Sowell, Erik De Clercq

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 323 KB

english, 2006

Antiviral Activities of New Cidofovir Analogs Against Camelpox Virus, Used as a Model of Variola Virus, in Human Skin Equivalent Cultures

Sophie Duraffour, Robert Snoeck, Joost Van Den Oord, Marcela Krecmerová, Antonín Holý, Jean-Marc Crance, Daniel Garin, Erik De Clercq, Graciela Andrei

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 61 KB

english, 2007

A pyrazolotriazolopyrimidinamine inhibitor of bovine viral diarrhea virus replication that targets the viral RNA-dependent RNA polymerase

Jan Paeshuyse, Carine Letellier, Matheus Froeyen, Hélène Dutartre, Robert Vrancken, Bruno Canard, Erik De Clercq, Alain Gueiffier, Jean-Claude Teulade, Piet Herdewijn, Gerhard Puerstinger, Frank Koene

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 407 KB

english, 2009

Design, synthesis and biological evaluation of cycloalkyl arylpyrimidines (CAPYs) as HIV-1 NNRTIs

Shuang-Xi Gu, Shi-Qiong Yang, Qiu-Qin He, Xiao-Dong Ma, Fen-Er Chen, Hui-Fang Dai, Erik De Clercq, Jan Balzarini, Christophe Pannecouque

Journal:

Golankiewicz, Bozenna, Ostrowski, Tomasz, Goslinski, Tomasz, Januszczyk, Piotr, Zeidler, Joanna, Baranowski, Daniel, de Clercq, Erik

Année:

2011

Langue:

english

Fichier:

PDF, 478 KB

english, 2011

Differential inhibition of various deoxyribonucleic acid polymerases by Evans blue and aurintricarboxylic acid

Hideo NAKANE, Jan BALZARINI, Erik de CLERCQ, Katsuhiko ONO

Journal:

FEBS Journal

Année:

1988

Langue:

english

Fichier:

PDF, 561 KB

english, 1988

Fluorescent Tricyclic Analogues of Acyclovir and Ganciclovir. A Structure−Antiviral Activity Study

Journal:

Deng, Bo-Liang, Hartman, Tracy L., Buckheit,, Robert W., Pannecouque, Christophe, De Clercq, Erik, Cushman, Mark

Année:

2001

Langue:

english

Fichier:

PDF, 87 KB

english, 2001

Replacement of the Metabolically Labile Methyl Esters in the Alkenyldiarylmethane Series of Non-Nucleoside Reverse Transcriptase Inhibitors with Isoxazolone, Isoxazole, Oxazolone, or Cyano Substituents

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 127 KB

english, 2006

Toward Improved Anti-HIV Chemotherapy: Therapeutic Strategies for Intervention with HIV Infections

Journal:

Jan Balzarini, Arthur Van Aerschot, Piet Herdewijn, Erik De Clercq

Année:

1995

Langue:

english

Fichier:

PDF, 6.27 MB

english, 1995

5-chloro-substituted derivatives of 2',3'-didehydro-2' ,3'-dideoxyuridine, 3'-fluoro-2' ,3'-dideoxyuridine and 3'-azido-2' ,3'-dideoxyuridine as anti-HIV agents

Journal:

Biochemical Pharmacology

Année:

1989

Langue:

english

Fichier:

PDF, 574 KB

english, 1989

Antiviral drugs in current clinical use

Journal of Clinical Virology

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 588 KB

english, 2004

Cidofovir in the therapy and short-term prophylaxis of poxvirus infections

Trends in Pharmacological Sciences

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 110 KB

english, 2002

Antiviral activity of diverse classes of broad-acting agents and natural compounds in HHV-6-infected lymphoblasts

Lieve Naesens, Pascale Bonnafous, Henri Agut, Erik De Clercq

Journal:

Journal of Clinical Virology

Année:

2006

Langue:

english

Fichier:

PDF, 572 KB

english, 2006

Antivirals: Past, present and future

Erik De Clercq, Richard T. Walker

Journal:

Biochemical Pharmacology

Année:

2013

Langue:

english

Fichier:

PDF, 383 KB

english, 2013

Synthesis and antiviral properties of 5-vinylpyrimidine nucleoside analogs

Journal:

Pharmacology & Therapeutics

Année:

1984

Langue:

english

Fichier:

PDF, 2.80 MB

english, 1984

Synthesis and antiviral activity of monofluorinated cyclopropanoid nucleosides

Rosen, Thomas C., De Clercq, Erik, Balzarini, Jan, Haufe, G�nter

Journal:

Organic & Biomolecular Chemistry

Année:

2004

Langue:

english

Fichier:

PDF, 230 KB

english, 2004

Organic Chemist Whose Inventions Reshaped the Antiviral Drug World

Medicinal Research Reviews

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 446 KB

english, 2013

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